Know LGMD
Limb-girdle muscular dystrophy (LGMD) is a group of genetic neuromuscular disorders that cause progressive muscle weakness, predominantly affecting the upper arms and legs ("limb") and the thoracic ("girdle") muscles.1,2
Genetic testing is essential to confirming subtype, guiding care, enabling clinical trial access, and helping monitor potential complications.3-5
LGMD affects more than strength4
LGMD includes 30+ subtypes with varying progression and systemic impact. Identifying the specific type, such as FKRP-related limb-girdle muscular dystrophy type 2I/R9 (LGMD2I/R9), is key to understanding the disease.1,3,4
LGMD2I/R9 MAY BE misdiagnosed3,6,7
Delays in diagnosis are common, which can impact care. Recognizing early signs helps guide appropriate next steps3,6
Signs and symptoms of LGMD2I/R9
Symptoms often develop gradually, affecting mobility, strength, and respiratory or cardiac function. Early recognition helps guide management.3,4